are endometrial stem cells novel tools against ischemic heart failure in women? a hypothesis
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منابع مشابه
Are Stem Cells the next Therapeutic Tool for Heart Repair?
Cardiovascular disease remains the leading cause of morbidity and mortality in the United States and Europe. In recent years, the understanding that regenerative processes exist at the level of the myocardium, has placed stem cell research at center stage in cardiology. A stem cell is a cell that has the ability to divide (self replicate) for indefinite periods often throughout the life of the ...
متن کاملWhat are Stem Cells?
Stem cells are undifferentiated self regenerating multi potential cells. There are three types of stem cells categories by the ability to form after cells and correlated with the body’s development process. Totipotent: these stem cells can form an entire organism such as fertilized egg. Ploripotent: ploripotent cells are those that can form any cell in the body but cannot form an entire organ...
متن کاملRegenerative Potential of Endometrial Stem Cells: A Mini Review
Recent findings in stem cell biology have opened a new window in regenerative medicine. The endometrium possesses mesenchymal stem cells (MSCs) called endometrial stem cells (EnSCs) having specific regenerative properties linked to adult stem cells. They contribute in tissue remodeling and engineering and were shown to have immuno-modulating effects. Many clinical trials were undertaken to asce...
متن کاملStem Cells in Heart Failure
Heart failure is a leading cause of morbidity and mortality in the developed world. Cardiac injury with a significant loss of cardiomyocytes usually leads to a common final pathway of cardiac pathological remodelling that includes fibrosis, and the development and progression of heart failure. The treatment of chronic heart failure generally relies on strategies designed to target and limit car...
متن کاملDeficiency in Clonogenic Endometrial Mesenchymal Stem Cells in Obese Women with Reproductive Failure – a Pilot Study
OBJECTIVES The mechanisms of obesity associated reproductive complications remain poorly understood. Endometrial mesenchymal stem-cells are critical for cyclic renewal and uterine function. Recently, W5C5(+) cells, with high clonogenicity, capable of producing endometrial stroma in vivo, have been described. We sought to investigate the abundance and cloning efficiency of W5C5(+) and W5C5(-) en...
متن کاملHeart Failure. Are Women Different?
The clinical syndrome of heart failure is very common in women. In fact, the majority of heart failure patients in the general population are female, in particular elderly women and women with a preserved ejection fraction. There are differences between heart failure in women and men in terms of epidemiology, pathogenesis, treatment response, and quality of care. The incidence is greater in men...
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عنوان ژورنال:
iranian red crescent medical journalجلد ۲۰۱۶، شماره ۱۱، صفحات ۷۳-۷۵
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